MORPHOFUNCTIONAL CHANGES IN THE RESPIRATORY LUNG DURING POSTNATAL DEVELOPMENT

Abstract

The aim of the study was to identify changes in the morphofunctional state of the respiratory part of the lungs in postnatal ontogenesis. The material for the study was the lungs of 23 rabbits aged from 1 to 180 days after birth. The respiratory department undergoes the most significant morphofunctional changes during early postnatal development. Lung acini in one- and ten-day-old animals have a primitive structure. From the fifteenth day, they expand the formation of alveolar passages and alveoli; in one-month-old rabbits, the structure of the acinus becomes almost the same as in adults. Argyrophilic and especially elastic fibers gradually thicken. Alkaline phosphatase activity is moderate in most periods of the study, increasing on days 7, 15 and 30 after birth. Gradually increases the number and thickens argyrophilic and especially elastic fibers.