NON-SPECIFIC INTERSTITIAL PNEUMONIA: DIFFERENTIATION OF INTERSTITIAL LUNG DISEASE FROM AUTOIMMUNE DISEASES

Abstract

Recent evidence suggests that nonspecific interstitial pneumonia (NSIP) has a distinct clinical feature among other idiopathic interstitial pneumonias, and some evidence points to a possible pathogenetic role for autoimmune immunity.
In the medical database of the Samarkand City Hospital No. 1, patients diagnosed with NSIP (n=58) were identified and after their initial examination, 32 cases of NSIP were identified and re-evaluated using a dynamic integrated multidisciplinary approach and a retrospective analysis was carried out.
The aim of this study was to evaluate whether NSIP might represent an early pulmonary manifestation of an autoimmune disease. >50% of patients diagnosed with NSIP developed clinical signs of autoimmune disease within 2 years, suggesting a possible link between NSIP and autoimmune disease.