MORPHOLOGICAL EVALUATION OF THE EFFECTIVENESS OF ANTIOXIDANT THERAPY OF DIETARY SUPPLEMENTS "GEPAVIT" ON THE MODEL OF HEAVY METAL POISONING IN THE EXPERIMENTAL CONDITIONS

Abstract

As you know, all living things are always directly or indirectly affected by various physical, mechanical, chemical or biological factors. These factors can cause pathomorphological and pathophysiological changes in the macroorganism of an individual, depending on the area or method of exposure to the body [11, 13].
Most living units in the biological food chain have the characteristics of an open system. The maintenance of the life form of these units is provided on the basis of respiration and nutrition [4, 2, 10].
The fact that the basis of life is food and water supply is substantiated by known biological knowledge [2, 3]. For this reason, micro- and macroelements in the food chain form the basis of all life processes and determine its existence in nature [5].
At present, almost all elements of the periodic system of chemical elements are involved in the metabolism of organisms. Interestingly, the majority of them are metallic elements. These elements can enter the body only through food mixtures from the external environment [8, 9, 14]. For this reason, if the number of elements in any food mixture exceeds the norm, then poisoning with this element occurs in the body. The degree of poisoning is necessarily proportional to the number and duration of exposure to the elements. For this reason, various poisonings that occur for a long time are referred to as chronic poisonings and lead to various stages of changes in the body [7].
Based on the foregoing, treatment of such poisonings with substances capable of biochemically oxidizing these elements, removing them from the body or converting them into other forms that are easily excreted without any harm is now widespread. They are usually called antioxidants [1, 6].
Antioxidant forms differ from each other in types and methods of application [15].