TUBERCULOSIS AND ASSOCIATED DISEASES

Abstract

The purpose of the study: to assess the impact of concomitant diseases on the course of tuberculosis, as well as to take a closer look at the statistical picture of tuberculosis in recent years. Materials and Methods: A literature review was conducted based on various monographs and textbooks on the research topic. Also, the statistical data of the World Health Organization for the last 5 years were analyzed. Analysis and discussion of results: Tuberculosis is one of the 10 leading causes of death in the world. According to the World Health Organization, up to 10 million people fall ill with tuberculosis every year in the world, of which about 1.5 million people die. In 82% of the examined patients with tuberculosis, diabetes mellitus was a previous background disease; the occurrence of tuberculosis in patients with peptic ulcer and duodenal ulcer complicates the course of both diseases. Conclusions: the use of a 4-month course of treatment for patients with drugsusceptible tuberculosis aged 12 years and older based on rifapentine, isoniazid, pyrazinamide and moxifloxacin, the use of a 4-month course of treatment for patients with mild tuberculosis aged 3 months to 16 years gives a high effect; the occurrence of tuberculosis in patients with peptic ulcer and duodenal ulcer is due to severe metabolic disorders caused by frequent exacerbations; the spread of the SARS-CoV-2 virus and ongoing epidemiological measures may affect the increase in the incidence of tuberculosis, which is associated with objective difficulties in detecting this infection against the background of COVID-19 and the development of complications after the disease.